Teevir is a complete,1-pill, once-a-day prescription medication by Mylan Pharma, used to treat HIV infection. It contains 3 antiretroviral agents: tenofovir disoproxil fumarate, emtricitabine, and efavirenz. Tenofovir disoproxil and Emtricitabine are both classified as nucleotide reverse transcriptase inhibitors. Efavirenz is, by contrast, is a non-nucleoside reverse transcriptase inhibitor. HIV is a retrovirus that targets the immune system, which is the system that fights off infection and disease. The virus damages or destroys white blood cells called CD4 cells. This makes it difficult for the body to fight off illness. Each drug included in Teevir tablets serves a unique purpose, but together they work to accomplish several important goals:
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Inbec, a fixed-dose combination drug that combines 3 antivirals into a single, once-daily pill is used to treat HIV. The tablet consists of an integrase strand transfer inhibitor (Dolutegravir 50 mg) with 2 nucleoside reverse transcriptase inhibitors (Abacavir 600 mg and Lamivudine 300 mg).
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Sofosbuvir is an HCV-fighting drug that is approved for the treatment of people with chronic hepatitis C virus infection. For 75-85 percent of people who contract the hepatitis C virus, it becomes a chronic infection that can lead to serious and life-threatening complications including liver failure, liver cancer, or liver transplantation. Sofosbuvir, in combination with other antiviral drugs, is a short-term therapy that has resulted in high cure rates. The clinical report noted that Sofosbuvir tablets improved sustained virologic response (SVR) rates up to 80%-90% while reducing the adverse events associated with treatment compared with the previous standard of care, which was a combination of pegylated interferon alpha and ribavirin.
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Spegra, once-a-day product to treat HIV/AIDS, combines 3 widely-used antiretroviral drugs Emtricitabine 200 mg, Dolutegravir 50 mg, and Tenofovir Alafenamide 25 mg in a single tablet. Taking just one daily combination pill instead of two, three, or four pills simplifies treatment for HIV-infected adults and potentially improves the ability of patients to adhere to treatment, which helps minimize the development of viral resistance.
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